This position is represented by SEIU Local 2007 and the collective bargaining agreement between the university and SEIU Local 2007 governs the terms and conditions of employment
The Czechowicz Lab within the Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, in the Department of Pediatrics at Stanford University School of Medicine is seeking a motivated, friendly and well-organized Life Science Technician III to perform basic functions and activities involved in various exciting research projects. This a dynamic and stimulating place to work, focused on excellence in research, education and patient care. The Czechowicz lab is focused on hematopoietic stem cell (HSC) biology and further exploring how HSCs interact with their microenvironment through basic science and translational medicine particularly in bone marrow transplantation with a focus on bone marrow failure syndromes to ultimately improve outcomes for these patients and many others.
Our laboratory has previously conducted pioneering work demonstrating that HSC depletion is a critical component to donor HSC engraftment. We have developed multiple pre-clinical agents that enable safe and targeted HSC conditioning, several of which are turning into promising clinical therapies that are now being tested in patients. We are now using these agents as probes to understand underlying hematopoietic biology and are applying these to the treatment of candidate diseases of great need. We are further augmenting this work with complementary efforts in therapeutic gene modification. We are primarily focused on genetic, cancerous and autoimmune blood and immune diseases, but this work could also potentially be expanded to other organ systems as well.
The lab strives to maintain a highly collaborative, dynamic and positive environment. The Life Science Technician III would be a great addition to the team and help with exciting basic and translational experiments that hopefully will result in exciting new therapies for patients.
Anticipated shifts: day shift M-F, weekends and holidays as needed
Duties include:
• Work with a great deal of independence when assisting the research team with animal (mouse)-based experiments. Coordinate with lab members and adhere to a timeline for animal experiments. Perform basic procedures such as peripheral bleeds and injections and prepare samples for further testing. Perform complex procedures such as bone marrow aspirates (surgical procedure) and interfemoral injections. They will be the key manipulator in the technical set-up and checkpoints of mouse in vivo experiments
• Work with veterinary team to ensure methods and procedures are optimal for health and safety of animals and share them with other members of the lab. Liaise with veterinary staff concerning care of experimental animals. Affix appropriate cards to animal cages to indicate special care concerning weaning and nutrition. Follow-up morbidity reports with veterinary staff. Ensure that animal protocols are updated with all planned experimentation and that these are followed by laboratory team. Alert veterinary staff of abnormal animal physical presentation/behavior
• Keep track of all experimentation in laboratory notebook and keep careful records of all animal use and animal breeding. Discuss this with lab manager and PI to ensure proper use and budgeting.
• Coordinate with lab members regarding general lab maintenance, supply inventory, and safety. Order animal equipment and supplies as needed. Coordinate use of equipment in animal facility.
• Check animal cages at least 3 times per week. Colony maintenance and genotyping. Set-up timed pregnancies for animals as required. At sacrifice, sample tissues and organs so that they are suitable for immunohistochemistry analysis and/or isolated cells according to the experimental needs defined with the PI.
• Train and orient a variety of technicians, students, and research staff in technical procedures and use of equipment. Assign, coordinate, evaluate, and provide guidance to lower-level technicians
The expected pay range for this position is $44.28 to $53.39/ hour.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location, and external market pay for comparable jobs. Placement in the pay range is also subject to the applicable Collective Bargaining Agreement.
• Bachelor’s degree in biology or related field
• Experience with mouse handling and experimentation with a minimum of 3 years of animal handling and relevant techniques (including breeding, intravenous/intraperitoneal injections, and sample collection)
• Collaborative with clear communication style and team-oriented mentality.
Three years’ experience at the Life Science Technician II level or equivalent combination of equivalent academic background and relevant work experience (e.g., three years of college science coursework).
• The Technician at the III level is required to have a higher degree of skill than the LST II (for independently performing highly skilled work) and sufficient knowledge of skilled procedures that s/he is able to troubleshoot problems which arise in either equipment or procedures.
• Technicians may also have highly specialized expertise in a particular technical area, or experience coordinating a variety of technical activities in a lab.
None
• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand.
• Ability to stand and move on hard surfaces for up to eight hours.
• Occasionally lift and handle materials up to 10 pounds
• Rarely carry/pull and/or push up to 20 pounds
• Must have correctible vision to perform duties of the job.
• Position may require repetitive motion.
* - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
Additional PHYSICAL REQUIREMENTS: (remove if none)
Work occurs in a research laboratory environment. Depending on research, may work in the vicinity of animals, chemicals, gasses, or hazardous materials. Expected to follow all safety requirements and procedures including wearing appropriate Personal Protective Equipment (PPE) if required.
Unusual working conditions:
• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
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