Life Science Research Professional 3

🔍 School of Medicine, Stanford, California, United States

New

📁: Research

📅   : 3 days ago Post Date

📅   : 106563 Requisition #

Stanford University is seeking a Life Science Research Professional 3 to perform complex functions and activities involved in defined research projects and independently conduct a major portion of the research project(s).

You will be working with an unparalleled leading-edge community of faculty and staff that are fundamentally changing the world of health care. You will have the opportunity to influence and drive change with your innovative ideas, the ability to make a difference, and participate in human advancements. Our culture is fast-paced, energetic, and growing all the time.

We offer a variety of benefits beyond traditional medical, dental, retirement, and savings options:

Events and programs for children, sports camps, and tuition options
World-class intellectual stimulation through learning and development classes, workshops, and onsite conferences from leading-edge speakers and faculty
Work/life and family-friendly policies and reimbursement
Participation in Stanford’s social responsibility and sustainable programs for a better world
A vibrant university culture that values the uniqueness of each individual

We are seeking candidates who are progressive thinkers, see challenges as simple problems to solve, and have the spirit and energy to change the world.

About the Department of Pathology:

The Department of Pathology at Stanford School of Medicine, one of its founding departments, stands as a leader among its peers nationwide. Our preeminent faculty spans from emerging leaders to highly accomplished physicians and scientists, including a Nobel laureate and members of the National Academy. Our mission is to improve the diagnosis, treatment, and basic understanding of human disease. This is done through discovery (research), education, and clinical care.

Comprised of extraordinary faculty and staff, our mission is to improve the ability to diagnose, treat and understand the origin and manifestation of human disease, and to care for those who have or are at risk of developing disease. We accomplish this through our clinical services (in all fields of anatomic and clinical pathology, including molecular and genomic pathology, histocompatibility testing and transfusion medicine) and research (which includes basic, translational and clinical research into the origins and manifestations of disease, including efforts to improve disease prediction and prevention as part of the goal of achieving precision medicine and health), and also by educating future leaders in pathology and related fields. Everything we do is to achieve the goals of providing the highest quality of clinical services to the patients for whom we passionately care, to advance our ability to understand, diagnose, monitor and ultimately to cure disease or to prevent or delay its occurrence, and to provide outstanding education and career development opportunities to those who share these goals.

For more information about the department visit http://pathology.stanford.edu/

About the Solomon Laboratory:

The Solomon Lab in the Department of Pathology at Stanford University School of Medicine and the Stanford Brain Tumor Center is a collaborative group of talented individuals who bring together diverse expertise in cell biology, genomics, and computational analysis to the study of brain and nerve sheath tumors. We employ the latest cutting-edge technologies including next-generation sequencing, genome-wide DNA methylation profiling, and genetically-engineered human cell models to advance the classification of and improve clinical outcomes for the many different types of brain and nerve sheath tumors. Our studies aim to reveal the mechanisms by which the different genetic alterations cause brain tumors to form, and how to better therapeutically intervene using a genomically-tailored precision medicine approach. We are currently particularly focused on a novel subtype of schwannoma nerve sheath tumors driven by indel mutations in the SOX10 transcription factor, gliomas arising in the setting of neurofibromatosis type 1 (NF1), and a novel molecular subtype of glioblastoma that we discovered.

About the Position:

The LSRP 3 position in the Solomon Laboratory in the Department of Pathology at Stanford University School of Medicine and the Stanford Brain Tumor Center will be part of a team of laboratory-based and computational-based scientists working together to make high-impact advances in the mechanistic basis of brain tumors that lead to new treatment avenues and cancer classification paradigms. Daily responsibilities of this wet lab position will include breeding and analysis of genetically-engineered mouse models of brain and nerve sheath tumors, development of cell culture models of human brain and nerve sheath tumors using primary human cells and patient-derived cell cultures with manipulation by CRISPR and lentiviral shRNA delivery, and basic biochemical and molecular biology methodologies including PCR, immunoblotting, and tissue culture.

Duties Include:

Design research approaches for a major portion of research project(s), including background research, experimental design and execution, problem solving, and writing up for publication.
Develop new protocols; test and evaluate a variety of approaches.
Conduct complex (lab and/or field) experiments, and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods.
Assist with new research proposals and applications for funding and grants.
Prepare periodic progress reports or written reports on all phases of the research project.
Lead or participate in multidisciplinary teams across different faculties or schools.
Contribute substantively to the preparation of papers for publication, especially in the results section. May be a co-author on publications. Present ongoing work and findings to colleagues at academic conferences.
Perform ongoing literature review to remain current with new procedures and related research; propose new research directions based on new advances discussed in literature.
Oversee supply and equipment budget under minimal supervision of principal investigator or business manager.
Work with the health and safety department to ensure the lab complies with regulations and all required trainings.
Formally supervise and train new staff or students as needed, including hiring, performance management, and related duties. Provide instruction on techniques and consultation on project work.

* - Other duties may also be assigned

Desired Qualifications:

PhD degree in related scientific field, such as Molecular Biology or Cancer Biology.
Experience with growth and genetic manipulation of primary human cell cultures and cell lines in vitro.
Experience working with recombinant mouse models, including breeding, husbandry, and tissue dissection.
Eagerness to participate in a team-science environment, working together with other talented individuals providing complementary expertise in computational data science and other modalities to answer complex problems in mechanistic disease-focused research.

Education & Experience (Required):

Bachelor's degree in related scientific field and four years of relevant work experience; or Master’s degree in a related scientific field and two years relevant experience; or PhD in related science field.

Knowledge, Skills, and Abilities (Required):

Comprehensive understanding of scientific principles.
Expert level knowledge and skills in field of science related to research project.
General computer skills, experience with databases and scientific applications, and ability to quickly learn and master computer programs.
Strong analytical skills and excellent judgment.
Ability to work under deadlines with general guidance is essential.
Excellent organizational skills and demonstrated ability to complete detailed work accurately.
Developing project management skills.

Physical Requirements*:

Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix, or operate hand and foot controls.
Must have correctable vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.

* - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Working Conditions:

May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.
Position is 100% onsite.

The expected pay range for this position is $93,062 to $111,670 per annum.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.

Why Stanford is for You

Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:

Freedom to grow. We offer career development programs, tuition reimbursement, or course auditing. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.
A caring culture. We provide superb retirement plans, generous time-off, and family care resources.
A healthier you. Climb our rock wall or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.
Discovery and fun. Stroll through historic sculptures, trails, and museums.
Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more

The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

Consistent with its obligations under the law, the university will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

Additional Information