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Grade: E
FTE: 100%
Stanford University is seeking a Life Science Research Professional 1 (LSRP1) to join our team and work on defined research projects focused on the development, maintenance, and plasticity of macrophage functions during persistent bacterial infection in the new laboratory of Dr. Trung Pham (https://profiles.stanford.edu/trung-pham?tab=bio). Under the guidance of the lead investigator, the LSRP will isolate immune cells from Salmonella-infected murine tissues for flow cytometry and functional assays, perform immunofluorescent imaging of tissues, cell culture, and cellular, molecular, and biochemical analyses. The position also will involve assisting with general lab maintenance. This is an opportunity to make significant contributions to a new laboratory and research program at Stanford. To apply to this position, please include a cover letter along with your resume in the online application system.
Research focus: Uncovering mechanisms of tissue immunity and immunophysiology during persistent infection: the metazoan immune system regulates tissue homeostasis, defends organisms against pathogens, and limits infection-induced tissue damages. Many pathogens, such as intracellular bacteria Salmonella enterica, Bartonella henselae, and mycobacteria can establish persistent infection and survive in host tissues for long periods of time. Using multidisciplinary approaches, we are interested in defining mechanisms that control tissue immune responses to contain pathogens and maintain physiologic activities during persistent infection, as well as to harness these mechanisms to eradicate persistent infection and restore tissue homeostasis.
Duties include:
· Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
· Independently conduct experiments; maintain detailed records of experiments and outcomes.
· Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
· Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
· Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
· Help with general lab maintenance and mouse colonies as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
· Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned